Prolific Machines is an Emeryville, California-based biotechnology company that applies optogenetics to biomanufacturing, using light-responsive proteins to dynamically control gene expression and protein production in living cells. Founded in 2020, it pairs optogenetic cell line development with add-on illumination hardware and data-driven process optimization that integrates with standard bioreactor infrastructure, serving biotechs, pharmaceutical companies and CDMOs through development services, platform licensing and CDMO partnerships. In 2026 the company reported an industry-record 21 g/L monoclonal antibody productivity in a 15-day intensified fed-batch CHO run.
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Oct 14, 2026
Latest raise
Funding activity · 1 round
Oct 14, 2026
$50M
Series B
Led by Atoms & Bits
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